MUSCLE FUNCTION & HOMEOSTASIS / MOLECULAR THERAPEUTIC APPROACHES
نویسندگان
چکیده
منابع مشابه
Novel Therapeutic Approaches for Skeletal Muscle Dystrophies
Muscular dystrophies (MDs) are inherited diseases that affect skeletal and cardiac muscle tissues. Cases range from mild to very severe, resulting in respiratory or cardiac failures. No cures are available for MDs and corticosteroid treatments, mainly deflazacort and prednisolone, only help to control the inflammatory process and slightly delay the progression of the disease. This is due to the...
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The functions of sleep remain elusive. Here, we review our current understanding of the evolution and ontogeny of sleep and demonstrate how comparative sleep research has contributed to our greater understanding of why we sleep. For instance, the occurrence of SWS and REM sleep exclusively in mammals and birds may be related to the convergent evolution of heavily interconnected brains and ass...
متن کاملTherapeutic considerations in respiratory muscle function.
Inspiratory muscle function is impaired in many patients with severe COPD. This functional impairment often leads to hypercapnic respiratory failure via inspiratory muscle fatigue. Factors responsible for this functional impairment are: (1) an excessive mechanical load (high resistance and low compliance) for the inspiratory muscles to overcome; (2) the low, flat configuration of the diaphragm ...
متن کاملNew therapeutic approaches for management of sport-induced muscle strains.
Muscle strains are one of the most common sports-induced injuries. Depending on the severity and location of the muscle strain, different treatment approaches can be taken. This review highlights recent trends in conservative, pharmacologic, and surgical approaches to the management of sports-induced muscle injuries as presented at a symposium held during the 93rd Annual Congress of the Italian...
متن کاملTherapeutic Approaches to Skeletal Muscle Repair and Healing
CONTEXT Skeletal muscle is comprised of a highly organized network of cells, neurovascular structures, and connective tissue. Muscle injury is typically followed by a well-orchestrated healing response that consists of the following phases: inflammation, regeneration, and fibrosis. This review presents the mechanisms of action and evidence supporting the effectiveness of various traditional and...
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ژورنال
عنوان ژورنال: Neuromuscular Disorders
سال: 2020
ISSN: 0960-8966
DOI: 10.1016/j.nmd.2020.08.070